Interventions for treating trichomoniasis in women

Cochrane Review by Forna F, Gülmezoglu AM

This record should be cited as: Forna F, Gülmezoglu AM. Interventions for treating trichomoniasis in women. Cochrane Database of Systematic Reviews 2007, Issue 4. Art. No.: CD000218. DOI: 10.1002/14651858.CD000218.

ABSTRACT

Title

Interventions for treating trichomoniasis in women

Background

Around 120 million women worldwide suffer from Trichomonas vaginalis vaginitis every year. The infection is sexually transmitted and is believed to facilitate HIV transmission.

Objectives

To assess the effects of various treatment strategies for trichomoniasis in women.

Search strategy

We searched the Cochrane Central Register of Controlled Trials , MEDLINE, and EMBASE. Trials were also identified from reference lists of reviews, through pharmaceutical companies, and by informal discovery. Only published data were used in this review. Date of the most recent search: November, 2002.

Selection criteria

Randomised or quasi-randomised trials of different treatment strategies in women with trichomoniasis. Different antitrichomonal drugs or doses were eligible, as were comparisons of treatment with no treatment or placebo.

Data collection and analysis

Trial quality was assessed and data extracted by two reviewers independently using standard criteria.

Main results

Fifty-four trials were included. Nitroimidazole drugs seem to be effective in achieving parasitological cure in short term follow up. Partner treatment can be effective in decreasing longer term reinfection rates.

Authors' conclusions

Parasitological cure can be achieved by single oral dose of nitroimidazole. Further research should focus on developing effective partner treatment strategies to prevent reinfections and reduce trichomoniasis prevalence.

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